What is the impact of high-performance computing (HPC) on companies and business?
On this page we introduce Estonian companies and academic users who have already benefited from the use of HPC.
Larger collections of inspiring HPC success stories from Europe are available on the FF4EuroHPC and FFplus webpages and on the HPC in Europe web portal.
Designing Faster Racecars with HPC-Powered CFD
Industrial organisations involved
Oldbac is an independent car manufacturer based in Estonia. They design and develop bespoke cars from the ground up — carbon-fibre monocoque, bespoke powertrain, and wind-tunnel validated aerodynamics. The Oldbac Kalana is a track-only sports car developed by Oldbac, and built in partnership with Italian coachbuilder Manifattura Automobili Torino. The car was created with the intention of setting a lap time of under 1:00 at the Porsche Ring, where it currently holds the outright record.
Technical/scientific challenge
To make a racecar fast, power and grip are essential. Physical grip is, however, constrained by the tires and the vehicle’s mass, but by using the airflow to push down (or rather sucking) the car into the ground, more grip can be achieved without adding mass to the car. By creating downforce from the passing air, significantly more grip can be achieved, enabling much higher cornering speeds and shorter braking distances.
Solution
The difficulty of solving advanced racecar aerodynamics stems from the fact that a racecar is essentially a collection of interacting, highly compromised bluff bodies operating in extreme ground effect. Unlike aerospace applications where flow is generally attached and steady, racecar aerodynamics is dominated by massive flow separation, chaotic wakes, and transient vortices. Around a lap, the car is also in many different states as the car pitches, rolls, yaws, and steers during cornering, braking, and acceleration. To ensure high performance, consistent downforce levels are needed during all these conditions. Vortices and wakes, therefore, need to be controlled to ensure that the airflow can consistently generate downforce on the track. This development can be done in a wind tunnel or virtually with Computational Fluid Dynamics (CFD). However, wind tunnels require a physical model, and their usage of them are expensive. Only a virtual model is required in CFD, making it possible to quickly evaluate many different concepts without any manufacturing. From the simulations, it is also possible to view and analyze the whole flow field, which helps the aerodynamicists to more quickly find ways to manipulate the airflow for more downforce.
Business impact
To simulate this type of advanced aerodynamics fine tuned CFD models are needed, to be able to well capture large to tiny details that affect the airflow. LUMI’s compute power capabilities enable us to solve simulations on grids consisting of several hundred million cells in a short time with high accuracy.
The vast compute power also makes it possible to evaluate many different concepts and driving conditions simultaneously. By using an open-source CFD package, no licenses are needed, making new designs and LUMI core availability the limiting factors. This makes it possible to develop the aerodynamics at a very high pace, and so far, several hundred designs have been evaluated, many in different driving conditions to ensure high-performing aerodynamics around the lap.
Benefits
- Faster, highly accurate simulations
- HPC allows to evaluate many different aerodynamic concepts and driving conditions, without having to manufacture physical prototypes
- Much faster development of high-performance aerodynamics
HPC-Accelerated Visual Navigation for Unmanned Ground Vehicles
Industrial organisations involved
Established in 2013, Milrem Robotics is the world-leading developer of robotics and autonomous systems and systems integrator. The company’s mission is to enhance combat effectiveness through advanced robotics. Milrem Robotics is leading the combat robotics industry with a broad depth of solutions to meet customers’ goals that go well beyond the hardware by offering capability development, experimentation and local industry integration, providing the customer with the least risk and greatest value.
Technical/scientific challenge
Milrem’s unmanned ground vehicles need to navigate off-road environments (forests, open terrain) using only passive sensors – camera and GNSS – with potentially outdated maps and unreliable satellite positioning. This requires training deep neural networks for both local obstacle avoidance from camera images and global path planning from overhead maps, involving multiple architecture comparisons and computationally intensive GPU training cycles.
Solution
A dataset of ~50 hours and 94 km of trajectories was collected from 47 sessions around Tartu, Estonia, together with georeferenced maps from multiple sources. Four local planner architectures (VAE, GNM, ViNT, NoMaD) and two global planner architectures were trained and compared on the University of Tartu HPC Centre’s GPU cluster. The system was validated both off-policy on recorded data and on-policy on a Jackal robot in indoor and outdoor environments.
Business impact
The solution applies to any domain requiring navigation in unstructured environments with poor GPS and outdated maps — defence, agriculture, forestry, and rescue operations. HPC resources enabled parallel training of multiple model architectures that would have been impractical on a single workstation. The open-source dataset also creates a foundation for a visual navigation benchmark and international robot orienteering competition, attracting new talent and solutions to Milrem Robotics.
Benefits
- Parallel training and comparison of 4+ neural network architectures, significantly accelerating the R&D cycle
- Processing and curation of a large-scale off-road navigation dataset (~50h video, 94 km trajectories, multiple map modalities)
- End-to-end proof-of-concept validated on a real robot, going beyond data collection to a working navigation demo
- Open-source codebase and dataset enabling future research and international collaboration
Speeding Up Cryo-EM Structural Analysis
Industrial organisations involved
Icosagen is Estonia’s largest biotechnology company with more than 26 years of experience. It provides integrated services across antibody discovery, antibody development, protein production, analytics, process development, and GMP manufacturing. Icosagen supports biopharmaceutical and biotechnology companies with end-to-end biologics development, from early research concepts to clinical manufacturing. Its “one-site, one-team, one-project” model is designed to reduce handovers, maintain traceability, and deliver consistent quality throughout development.
Technical/scientific challenge
Icosagen’s antibody development work includes complex antibody formats and draws on expertise in structural and computational biology. In this context, detailed structural insight is important for understanding molecular interactions and supporting antibody optimization.
Icosagen mainly uses RELION software to process cryo-EM data for solving antibody–antigen complexes. These workflows involve computationally intensive steps such as large-scale image processing, 2D and 3D classification, iterative refinement, and reconstruction. When multiple datasets must be processed in parallel, standard computing environments can become a bottleneck, slowing analysis and limiting throughput.
Solution
To address this challenge, Icosagen uses an HPC computing cluster to run RELION-based cryo-EM processing workflows. HPC resources provide the compute capacity needed to handle demanding reconstruction and refinement jobs more efficiently and to process multiple projects at the same time.
By moving cryo-EM processing to the cluster environment, Icosagen can accelerate the path from raw microscopy data to interpretable antibody–antigen structures. This supports a more scalable structural biology workflow and enables cryo-EM analysis to fit more effectively into the company’s broader antibody discovery and development pipeline.
Business impact
HPC strengthens Icosagen’s integrated biologics development model by adding scalable computational power to its in-house scientific capabilities. Icosagen already provides a broad range of antibody and protein development services, and faster structural analysis improves the company’s ability to support customer projects that require detailed molecular characterization.
For antibody-focused projects, quicker cryo-EM turnaround helps teams move faster from experimental data to structure-based interpretation. This improves responsiveness in research and development, supports more efficient decision-making, and increases the capacity to handle structurally demanding projects alongside other services delivered by Icosagen.
Benefits
- Faster processing of cryo-EM datasets for antibody–antigen complex structure determination
- Ability to run multiple RELION jobs and datasets in parallel
- Shorter analysis cycles from raw data to structural insight
- Better scalability for computationally demanding structural biology workflows
- Stronger support for antibody discovery, development, and characterization projects
Aerodynamic development of Formula Student race car
Industrial organisations involved
The Formula Student is an international product development competition aimed for the students of engineering and automotive technology. Formula Student Team Tallinn designs, manufactures and competes a high-performance formula car every year, utilizing cutting-edge technology and engineering principles. The car participates in Formula Student product development competitions all over Europe. Formula Student Team Tallinn has been driving the race since 2006. The team has won numerous trophies from all around the world.
Technical/scientific challenge
Aerodynamical development requires solving computational fluid dynamics (CFD) simulations. External aerodynamics, the type of flow which cars encounter require big domains to reduce interference and very small element sizes near the object (car) surface to capture the flow structures as accurately as possible. Due to these two criteria, the solved mesh sizes become very big ( cells). As every cell needs to have its value calculated for every iteration and a single simulation will run up to 1000 iterations, a household computer is no longer sufficient for the task and HPC capabilities are required.
Solution
The HPC interfaces allow us to transfer the created simulation files to the HPC centres, where a batch job can be created and the HPC hardware will be used to calculate the values of the equations given by the simulation files. Once the simulation files have been solved, they will be saved and are available for the user to download. With almost zero time wasted on the users personal computer, the solved file can be downloaded and reviewed by the engineer, to then design and simulate a next design iteration.
Business impact
The HPC saves huge amount of available computer time on the users personal computer, as running a 3D aerodynamics simulation will vacate a well specced computer up to a day, rendering it essentially useless. The HPC capabilities also increase the speed of development significantly, since the simulations run faster and multiple simulations can be solved at the same time. Additionally, bigger and therefore more accurate files, which require huge amounts of RAM could be solved only with the HPCs. These aspects hugely improve the aerodynamic development process of our formula student team and allow us to reach the highest of stages.
Benefits
- Increased work rate - multiple concurrent simulations and faster solving times allow roughly 20x more simulations to be run
- Increased accuracy of simulations, as more accurate models can be used, which require high computing power
- More efficient time usage of the engineer - post-processing and other tasks can be solved while the simulations are running
HPC-Powered DNA Metagenomics to Fight Honey Fraud
Industrial organisations involved
Celvia is an Estonian company and research institution owned by the University of Tartu, the University of Tartu Hospital and the Nova Vita Clinic, among others. Celvia’s mission is to develop and deliver innovative science-based products and services for patients, clinicians and businesses. The company combines new knowledge with state-of-the-art technology and unique skills, resulting in competitive genetic tests that meet high standards. They collaborate with researchers and clinicians from Estonia and abroad to ensure the high quality of basic research.
Technical/scientific challenge
Honey contains approximately 0.01% DNA, which can be extracted and sequenced to produce up to 20 million DNA sequencing reads. These sequences can be computationally analysed using a taxonomic classifier to get insights into the biological composition of honey, aid in monitoring honeybee pathogens, and assess authenticity. However, this computational analysis is resource-intensive as the taxonomic classifier alone relies on a database approximately 400 GB in size, and the analysis involves multiple steps. The company needs to process a high volume of samples on a weekly basis.
Solution
Using high-performance computing (HPC), the company processes 32 samples in parallel through a singularity-containerized Nextflow workflow comprising seven subtasks. The most resource-intensive subtask demands 400 GB of RAM and 8 CPUs per sample. To streamline operations, they have automated the detection of new data, downloading, and initiation of analysis using crontab. Additionally, HPC resources are utilized to securely store raw data and analysis results, ensuring data integrity and confidentiality with backup systems in place.
Business impact
Honey is one of the most commonly counterfeited foods, creating a significant global challenge. Counterfeit honey is produced at a fraction of the cost of authentic honey, driving down market prices and threatening the livelihoods of honest beekeepers. To address this issue, HPC solutions offer the computational power necessary to analyse large volumes of honey samples on a weekly basis. These analyses help combat honey fraud by verifying authenticity and providing valuable taxonomic insights, enabling beekeepers to better understand and protect the quality of their honey and monitor the health of honeybees.
Benefits
- HPC computational resources enable rapid processing of large volumes of weekly samples for honey analysis service, reducing results reporting time
- Automation of the analysis process eliminates the need for specialists, allowing office staff to simply download results when notified
- With petabytes of secure storage, HPC ensures safe data storage, including backups and access restrictions
Driving Efficiency in Radiology Workflows with Intelligent Insights
Industrial organisations involved
Better Medicine is an Estonian medical technology company founded in 2020 that focuses on applying artificial intelligence in radiology to detect oncological findings. Unlike traditional single-organ AI solutions, Better Medicine adopts a holistic, multi-organ approach, streamlining cancer diagnostics to aid in detecting primary tumours, metastases, and unidentified disease. The company’s mission is to transform the landscape of cancer diagnostics and radiology, reducing the burden on professionals and improving outcomes of cancer patients.
Technical/scientific challenge
Better Medicine faces the challenge of efficiently training advanced AI models for lesion detection, measurement, and segmentation from CT scans. This requires substantial computational power to handle large datasets, optimize model performance, and reduce training time.
Solution
Using the HPC Centre at the University of Tartu, Better Medicine leverages high-performance GPUs enabled nodes and scalable infrastructure to train deep learning models on large imaging datasets. The computational resources enable faster experimentation, precise parameter optimization, and the development of robust AI models ready for clinical use.
Business impact
HPC resources significantly enhance the speed and accuracy of Better Medicine’s AI models, enabling rapid iteration cycles and model improvements. These models accelerate radiological workflows by automating lesion segmentation and measurement, addressing the global radiologist shortage, and expediting patient care. The adoption of HPC supports scalability, ensuring efficient handling of increasing data volumes as Better Medicine expands its solutions to broader clinical applications.
Benefits
- Reduced model training time from weeks to days
- Improved AI model performance via rapid iteration cycles
- Enhanced scalability for future clinical datasets
- Enabling accelerated patient care through automated workflows
Machine Translation for Low-resource Finno-Ugric Languages
Scientific partners involved
The University of Tartu is the leading university in the Baltics in the field of information technology and is one of the 250 best universities in the world in the ranking of Times Higher Education Universities in the field of Computer Science. Examples of the University’s Chair of Natural Language Processing’s research directions include machine learning and data mining on text data, machine translation from one natural language into another, summarization of a long text document, automatic analysis of grammatical correctness, word meanings and sentence structure.
Technical/scientific challenge
Neural networks have caused rapid growth in output quality for many natural language processing tasks, including neural machine translation (NMT). However, the output quality crucially depends on the availability of large amounts of parallel and monolingual data for the covered languages. Due to lack of training material, several lower-resource Finno-Ugric languages are not included in the existing massively multilingual models. In terms of the number of speakers, they range from 20 near-native speakers of Livonian to several hundred thousand speakers of Mordvinic languages.
Solution
An NMT system was developed between 20 low-resource Finno-Ugric languages and 7 high-resource languages. Monolingual corpora was collected mainly by crawling texts off the web and combining with pre-existing corpora. Three main categories of texts can be distinguished: news, Wikipedia, and biblical. All the NMT systems were trained on the LUMI supercomputer. All models were fine-tuned with the Fairseq framework implementation of M2M-100 for 350k updates with a batch size of 3840 tokens (the number was chosen to match earlier versions of models trained with the Huggingface implementation of M2M-100). The models were fine-tuned on 4 AMD Mi250X GPU-s.
Scientific impact
More that 20 Finnish-Ugric languages can now be translated using the machine translation engine of the University of Tartu. Most of these languages were added to a public translation engine for the first time. The translation engine allows researchers to translate materials that would otherwise be incomprehensible to them. It provides an opportunity to better study the history of languages and regions without knowing the respective language. Moreover, since most of Finno-Ugric languages are not widely spoken today, a translation engine is necessary to preserve these languages.
Benefits
- Collection of parallel and monolingual corpora that can be used for training NMT systems for 20 low-resource Finno-Ugric languages
- Expansion of the 200-language translation benchmark FLORES-200 with manual translations into nine new languages (Komi, Udmurt, Hill and Meadow Mari, Erzya, Livonian, Mansi, Moksha and Livvi Karelian)
- The collected data can be used to create NMT systems for the included languages and investigate the impact of back-translation data on the NMT performance for low-resource languages
Cosmic Ray-based Solutions for 3D Imaging
Industrial organisations involved
GScan was founded in 2018 to revolutionise inspection, security and medical scanning markets using Muon Flux Technology (MFT). GScan, as the pioneer of MFT having unique IP, tech & sales know-how in the field, is developing a new generation of Non-Destructive Testing (NDT) scanners and tomography systems for infrastructure management applications.
Technical/scientific challenge
In 1968, Soviet Union built a nuclear submarine training base with two full-length submarines next to Estonian town of Paldiski. The site was handed over to the Estonian authorities, but no detailed specifications about the site were offered. The reactors and radioactive waste have been buried in concrete within the submarine bodies, which are further surrounded by a concrete sarcophagus. 3D scanning, mapping, and performing atomic detection of the now-defunct nuclear reactors were required to decommission these submarines safely.
Solution
Capitalising on the power of natural cosmic ray tomography, the technology tracks the trajectory changes or absorption of particles (muons, electrons, positrons) as they pass through the object of interest, thereby extracting crucial statistics about its material and shape. These insights are then translated into 2D and 3D visualisations of both internal and external geometries, along with data on chemical composition. The comprehensive output we deliver provides in-depth insights into the objects and materials under scrutiny – all meticulously tailored to fulfil our customers’ unique requirements. HPC plays an important role in translating the collected data into visualisations.
Business impact
GScan’s muFLUX Infra detectors can be used for 3D imaging of abandoned nuclear reactors to ensure the safe decommissioning process. In order to minimise the risks of dismantling the site, a high-resolution 3D image and atomic composition analysis is needed. With time and space related digital data in terabytes, the detailed process of reconstruction enables to see inside of structures what was not possible before.
Benefits
- Because HPC accelerates data processing, reconstructions are completed in less time.
- With faster reconstruction it is possible to apply wider range of algorithms during the post processing
- With a wider range of algorithms the capability and efficiency of the technology grows and with better muon flux technology the world can become safer thanks to more reliable data about critical infrastructure
Machine Translation Post-Editing
Industrial organisations involved
Luisa Tõlkebüroo OÜ is the biggest translation agency in Estonia. The company offers more than 50 services – including sworn translation, simultaneous and consecutive interpretation, layout work, machine translation and post-editing, subtitling and localisation.
Technical/scientific challenge
The company needed a custom-made machine translation system to reduce the time of translations. They had lots of proprietary domain-specific data but no NLP competence nor the infrastructure required for training.
Solution
As the company had no previous experience neither in natural language processing nor in machine learning, they collaborated with the TartuNLP team. Training of the machine translation model was conducted by using University of Tartu HPC centre’s Rocket cluster with plenty of GPU resources.
Business impact
Thanks to rapid advances in the technology and extensive translation memory, the company is able to offer machine translations with post-editing in a range of language combinations and on a range of topics. Moreover, the company realized that there was no need to invest in their own infrastructure as the model was deployed the in HPC centres’s cloud.
Benefits
- The innovative translation tool helps to save valuable time and human resources
- Creation of high quality reference dataset for future developments.
- Lower deployment costs and no need to worry about maintaining own hardware
An accurate AI-based Cloud Mask Processor for Sentinel-2
Industrial organisations involved
KappaZeta is a science-driven remote sensing company aiming to make space a valuable asset for everyone. KappaZeta’s expertise is in using SAR (radar) satellite data, incorporating it with optical satellite data and providing some of the most accurate AI models on the market. The key area of focus is agriculture.
Technical/scientific challenge
Cloud masking is an essential step for the pre-processing of optical satellite imagery. KappaZeta addresses the problem by introducing KappaMask, an AI-based cloud and cloud shadow masking processor for Sentinel-2, which carries an optical instrument payload that samples 13 spectral bands. As a cloud detector, KappaMask uses a large convolutional segmentation model. Faster model convergence during training can be achieved by using larger batch sizes of the training data, which means more GPU memory is needed. Additionally, faster CPUs are required for shorter data loading times to increase the training speed even further.
Solution
KappaMask was trained on an open-source dataset and fine-tuned on a Northern European terrestrial dataset which was labelled manually using the active learning methodology. The training was performed on the University of Tartu’s HPC Centres’ high-performance compute nodes. Powerful GPUs and CPUs were applied to substantially speed up the training of the model.
Business impact
KappaMask is an open source project. All the results, final software and source code will be freely and openly distributed in GitHub. Openness and accessibility of the software should directly translate into greater usage.
Benefits
- Reliable cloud mask processor for Northern Europe region, which is compatible with ESA Sentinel-2 L2 processing chain.
- Creation of high quality reference dataset for future developments.
- Innovative application of deep learning techniques in cloud masking.
Self-driving technology for a Level 4 autonomous car
Industrial organisations involved
Bolt is an Estonian mobility company that offers vehicle for hire, micromobility, car-sharing, and food delivery services headquartered in Tallinn and operating in over 400 cities in over 45 countries. In partnership with the University of Tartu, the company developes self-driving technology for a Level 4 autonomous car.
Technical/scientific challenge
Autonomous cars acquire up to 357 GB/hour of data during test drives. Autonomous car engineers needed a system to store and easily access those test logs.
Solution
Acquired test logs are copied to HPC storage, into appropriately guarded directory. Regularly cron job processes those log files into metadata stored in MongoDB database. Processing is distributed over cluster and happens in parallel. Longest logs can take up to 24 hours to process, so processing them sequentially would be very time-consuming. On top of MongoDB sits custom-made application that allows filtering of test sessions and browsing them using Webviz visualization tool. Visualization tool accesses the raw sensor data from HPC storage.
Business impact
With the growing demand for ride-hailing services, autonomous vehicle technology will provide a solution for transportation problems on an increasingly broader scale.
Benefits
- Custom database application and visualization tool enables easy analysis of the logs
- Thanks to distributed processing in the cluster the metadata about the drives usually shows up already next morning
- Thanks to petabytes of storage at the HPC Centre, the company can keep all the data they need
